Cannabidiol as a Neuroprotective Agent in Acrylamide‐Induced Neurotoxicity: Effects on Oxidative Stress, Inflammation, and Cholinergic Function in Male Mice

Abstract The neuroprotective potential of cannabidiol (CBD) was assessed in a mouse model of acrylamide‐induced neurotoxicity. Acrylamide (AA), an environmental and dietary pollutant, is known to cross the blood–brain barrier and induce oxidative stress, inflammation and neurotoxic effects. Male C57BL/6 mice were randomly assigned to four groups: Control (Con), Acrylamide (AA), Cannabidiol (CBD), and a combination treatment (AA + CBD). The AA group received acrylamide (10 mg/kg, i.p.) daily for 5 days. CBD was administered (10 mg/kg, i.p.) for 10