Dose-dependent effects of cannabidiol in drinking water on yolk fatty acid profile and hepatic expression of polyunsaturated fatty acids (PUFAs) -related genes in laying hens: insights into the cannabidiol (CBD) systemic and molecular mechanisms of action

Abstract Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1186/s12917-025-05122-y. Article type: Research Article Keywords: Cannabidiol (CBD), Laying hens, Yolk deposition, Lipid metabolism, Gene expression Authors: Sepideh Fallahi, Agnieszka Śmieszek, Łukasz Bobak, Anna Lipińska, Muhammad Umair Asghar, Katarzyna Olejnik, Sebastian Opaliński Affiliations: https://ror.org/05cs8k179grid.411200.60000 0001 0694 6014Department of Environmental Hygiene and Animal Welfare, Wrocław University of Environmental and Life Sciences, Wrocław, 51-630 Poland; https://ror.org/05cs8k179grid.411200.60000 0001 0694 6014Department of Pharmacology and Toxicology, Wrocław University of Environmental and Life