Constructing a chemokine-based model and identifying CCL17 as a core biomarker associated with immune infiltrates in thyroid cancer

Abstract Background: Recent studies have highlighted the crucial role of chemokines in tumor progression and immune regulation, particularly in thyroid cancer (THCA). This study aims to construct a prognosis model related to chemokines and identify a potential biomarker in THCA. Methods: Hub genes were identified for a risk model construction using Cox analysis, which was evaluated by the Kaplan-Meier (K-M) and receiver operating characteristic (ROC) curves. Enrichment analyses were used for functional annotation. CIBERSORT was used to calculate the immune