The predictivity of hematological parameters and related inflammatory biomarkers of male subjects with chronic polysubstance use disorder

Abstract Background: Polysubstance use disorder (PSUD) is a chronic disease with adverse clinical outcomes. Hematological properties and related inflammatory biomarkers have not been investigated in PSUD. This study aimed to investigate the alterations in hematologic and related inflammatory parameters among subjects with PSUD. Methods: A total of sixty subjects were included, thirty chronic PSUD subjects and thirty control subjects. Venous blood was withdrawn from participants, and complete blood count was conducted. Related inflammatory biomarkers were calculated, including neutrophil-to-lymphocyte ratio (NLR),