Elucidating interplay between myrcene and cannabinoid receptor 1 receptors to produce antinociception in mouse models of neuropathic pain

Abstract Myrcene, a terpene found in cannabis, dose-dependently attenuated allodynia associated with nerve injury by engaging CB1 receptors without producing negative reinforcement or direct activation of cannabinoid receptor 1 receptors. Article type: Research Article Keywords: Terpenes, Neuropathic pain, Cannabinoid 1 receptor Authors: Myra Alayoubi ⚬, Akeesha Rodrigues, Christine Wu, Ella Whitehouse, Jessica Nguyen, Ziva D. Cooper ⚬, Patrick R. O’Neill, Catherine M. Cahill ⚬ Affiliations: UCLA, Neuroscience Interdepartmental Graduate Program, University of California, Los Angeles, Los Angeles, CA, United States;