When coronary spasm strikes: a case report on the dreadful association between cannabinoids and caffeine

Abstract Background: Coronary artery spasm (CAS) is a temporary, severe narrowing of the coronary arteries typically presenting with nitrate-responsive angina at rest, transient ischaemic ECG changes, and in some cases leading to silent myocardial ischaemia, acute myocardial infarction, life threatening arrhythmias and cardiac arrest. Case Summary: A 47-years-old man with a history of chronic coronary syndrome and a working diagnosis of probable pheochromocytoma was admitted to the Emergency Department after two episodes of out-of-hospital cardiac arrest successfully resuscitated. Transient ST