Abstract Background: Chronic kidney disease (CKD) is a highly prevalent global public health problem that inevitably leads to renal failure.…
Abstract Endocannabinoids (eCBs) are lipid-derived neuromodulators that regulate numerous neurophysiological processes by modulating synaptic transmission. Synthesised on demand in response…
Abstract Introduction: RRN3 is a nucleolar protein required for ribosome biogenesis, but its role in cancer remains insufficiently defined. This…
Abstract Obstructive sleep apnea (OSA) is a sleep-disordered breathing condition characterized by recurrent upper-airway obstruction, leading to intermittent hypoxemia, sleep…
Abstract Highlights: Article type: Research Article Keywords: arthritis, cannabis, decision making, decision support intervention, older adults, shared decision making Authors:…
Abstract Introduction: COVID-19 created major disruptions worldwide, including significant effects on education. Nursing programs shifted rapidly to online learning and…
Abstract Pancreatic cancer (PC) is one of the deadliest cancers, largely because it is often detected late and responds poorly…
Abstract Background: Periodontitis is a chronic inflammatory disease characterized by dysbiotic biofilm formation, progressive destruction of periodontal tissues, and alveolar…
Abstract Background: While secreted phosphoprotein 1 (SPP1) drives macrophage M2 polarization and cancer progression in multiple malignancies, its role in…
Abstract Background: Immune-related snoRNAs remain largely uncharacterized in cancer. Methods: We comprehensively investigated their functions and clinical relevance through an…
Abstract Background: Cannabidiol (CBD) has emerged as a promising adjunctive therapy for drug-resistant epilepsy, yet clinical findings remain heterogeneous across…
Abstract Neuropsychiatric disorders represent a significant global health burden. Despite decades of research, current treatments typically provide only symptomatic relief,…
Abstract Human epidermal growth factor receptor 2-positive (HER2+) breast cancer, accounting for 15% to 20% of cases, is often resistant…
Abstract Background: Intratumor heterogeneity (ITH) plays an important role in patients’ clinical outcomes. The prognostic impact of ITH and its…
Abstract Hemp (Cannabis sativa L.) is a multipurpose crop with significant industrial and therapeutic potential. This article reviews the various…
Abstract Comorbid substance use disorders (SUDs) are common but difficult to study due to the complex, interacting and overlapping mechanisms…
Abstract Background: Altered lipid metabolism is increasingly recognized as a driver of tumor progression, yet its specific role in thyroid…
Abstract Following the passage of the Agriculture Improvement Act of 2018, demand for accurate cannabinoid quantification in hemp flowers has…