Abstract Background: Glutamine metabolic reprogramming is a hallmark of tumor progression and is highly correlated with poor clinical outcomes. The…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-74808-4. Article type: Research Article Keywords: LAG3, Immune checkpoint,…
Abstract Objective: It has been demonstrated that IDO1, a target of immune checkpoint inhibition, functions as an oncogene in the…
Abstract Objective: PD-L1, a target of immune checkpoint blockade, has been proven to take the role of an oncogene in…
Abstract Background:CD27 is an immunological checkpoint gene, plays a critical function inInhibition or activation of cancer immunity. The CD27/CD27L axis…
Abstract Background: The immunological checkpoint known as Inducible T Cell Costimulatory Factor (ICOS, Cluster of Differentiation, CD278) is activated and…
Abstract Background: Dual homeoboxes A pseudogene 8 (DUXAP8) is a newly discovered long noncoding RNA that has been shown to…
Abstract Background: Although combination therapies have substantially improved the clinical outcomes of cancer patients, the prognosis and early diagnosis remain…