Pan‐cancer analysis reveals sex‐specific signatures in the tumor microenvironment
Abstract The processes of cancer initiation, progression, and response to therapy are affected by the sex of cancer patients. Immunotherapy…
Wang-Yang Yang
Integrative analysis of the molecular mechanisms, immunological features and immunotherapy response of ferroptosis regulators across 33 cancer types
Abstract Ferroptosis is a recently described mode of cell death caused by the accumulation of intracellular iron and lipid reactive…
The complete chloroplast genome of Cannabis sativa variety Yunma 7
Abstract Cannabis sativa variety Yunma 7 has been widely cultivated for hemp fiber production in Yunnan Province of China. In…
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Abstract The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome…
Divergent mutational processes distinguish hypoxic and normoxic tumours
Abstract Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular…
Comprehensive molecular characterization of mitochondrial genomes in human cancers
Abstract Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome…