Abstract Purpose: Off-target binding remains a significant challenge in tau-PET neuroimaging. While off-targets including monoamine oxidase enzymes and neuromelanin-containing cells…
Abstract Background and objective: Non-motor symptoms frequently develop throughout the disease course of Parkinson’s disease (PD), and pose affected individuals…
Abstract Tauopathies are a heterogeneous group of neurologic diseases characterized by pathological axodendritic distribution, ectopic expression, and/or phosphorylation and aggregation…
Abstract Highlights: Abstract: Neurodegenerative parkinsonian disorders are characterized by a great diversity of clinical symptoms and underlying neuropathology, yet differential…