Structural basis for the synergistic assembly of the snRNA export complex
Abstract The nuclear cap-binding complex (CBC) and its partner Arsenite-Resistance Protein 2 (ARS2) regulate the fate of RNA polymerase II…
Stephen Cusack
Structural snapshots of phenuivirus cap-snatching and transcription
Abstract Severe fever with thrombocytopenia syndrome virus (SFTSV) is a human pathogen that is now endemic to several East Asian…
NCBP3 positively impacts mRNA biogenesis
Abstract The nuclear Cap-Binding Complex (CBC), consisting of Nuclear Cap-Binding Protein 1 (NCBP1) and 2 (NCBP2), associates with the nascent…
Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition
Abstract RIG-I is a viral RNA sensor that induces the production of type I interferon (IFN) in response to infection…