Temporal-iCLIP captures co-transcriptional RNA-protein interactions
Abstract Dynamic RNA-protein interactions govern the co-transcriptional packaging of RNA polymerase II (RNAPII)-derived transcripts. Yet, our current understanding of this…
Sander Granneman
The Nrd1-like protein Seb1 coordinates cotranscriptional 3′ end processing and polyadenylation site selection
Abstract Here, Lemay et al. investigated whether the mechanism of transcription termination is evolutionarily conserved in S. pombe. They show…
A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation
Abstract The assembly factor heterodimer Rsa4–Nsa2 binds to the preribosome and transmits remodeling energy from the force-generating ATPase Rea1 to…