A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation

Abstract The assembly factor heterodimer Rsa4–Nsa2 binds to the preribosome and transmits remodeling energy from the force-generating ATPase Rea1 to facilitate relocation of ribosomal RNA elements during ribosome maturation. Authors: Jochen Baßler, Helge Paternoga, Iris Holdermann, Matthias Thoms, Sander Granneman, Clara Barrio-Garcia, Afua Nyarko, Gunter Stier, Sarah A. Clark, Daniel Schraivogel, Martina Kallas, Roland Beckmann, David Tollervey, Elisar Barbar, Irmi Sinning, Ed Hurt Affiliations: Biochemistry Center of Heidelberg University, INF328, D-69120 Heidelberg, Germany; Centre for Synthetic and Systems Biology (SynthSys)