Transgenerational effects of perinatal cannabis exposure on female reproductive parameters in mice
Abstract The use of cannabis during pregnancy and nursing is a growing public health concern, and the multigenerational impacts of…
Ryan J. McLaughlin
Sex differences in adolescent cannabis vapor self-administration mediate enduring effects on behavioral flexibility and prefrontal microglia activation in rats
Abstract Cannabis is the most used illicit drug in the United States. With many states passing legislation to permit its…
Pharmacokinetics and central accumulation of delta-9-tetrahydrocannabinol (THC) and its bioactive metabolites are influenced by route of administration and sex in rats
Abstract Up to a third of North Americans report using cannabis in the prior month, most commonly through inhalation. Animal…
Cannabis vapor self-administration elicits sex- and dose-specific alterations in stress reactivity in rats
Abstract Rationale: Cannabis users frequently report stress relief as their primary reason for use. Recent studies indicate that human cannabis…
Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain
Abstract Low dose of cannabidiol ameliorates mechanical allodynia and anxious behavior and restores impaired serotonergic transmission in a neuropathic pain…