Abstract Background: Ovarian cancer (OV) poses a significant challenge in oncology due to its complex molecular mechanisms and poor prognosis.…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-31042-w. Article type: Research Article Keywords: Pan-cancer, E2F family,…
Abstract The cap-binding protein complex (CBC), comprising Cbp20 and Cbp80, is crucial for gene expression, yet its role in the…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s40364-024-00652-3. Article type: Review Article Keywords: METTL protein family,…
Abstract Background: In the realm of tumor-targeted therapeutics, Polo-like kinases (PLKs) are a significant group of protein kinases that were…
Abstract TGFβ signaling is associated with non-response to immune checkpoint blockade in patients with advanced cancers, particularly in the immune-excluded…
Abstract Background: The role of CIA‐II has been clarified in several types of tumors; however, whether dysregulated CIA‐II expression is…