Pan-Cancer Analysis of the Prognostic and Immunological Role of ECT2: A Promising Target for Survival and Immunotherapy
Abstract Objectives: The aim of this study is to investigate the role of epithelial cell transforming sequence 2 (ECT2) as…
Lulu Wang
Exploration of the carcinogenetic and immune role of CHK1 in human cancer
Abstract Background: Previous study indicated that CHK1 was important for repairing DNA damage and cell cycle regulation. Aims: To investigate…
Single-cell transcriptomics reveals the role of antigen presentation in liver metastatic breast cancer
Abstract Liver metastasis (LM) is the primary cause of cancer-related mortality in late-stage breast cancer (BC) patients. Here we report…
Correlation analysis of positron emission tomography/computed tomography-magnetic resonance imaging of cannabinoid type 1 receptor in the lumbar spine and brain of aged osteoporosis female cynomolgus monkeys
Abstract Background: Although cannabinoid receptor 1 (CB1R) antagonists can inhibit bone loss in osteoporosis mouse models, different strains of mice…
Exploring the immunological role and prognostic potential of PPM1M in pan-cancer
Abstract Methods: Samples of cancer and normal tissues were obtained from the cancer genome atlas and genotype-tissue expression. Kaplan–Meier survival…
A Comprehensive and Systematic Analysis Revealed the Role of ADAR1 in Pan-Cancer Prognosis and Immune Implications
Abstract Adenosine deaminase RNA specific 1 (ADAR1) has been identified as an enzyme that deaminates adenosine within the dsRNA region…
Whole-genome resequencing of wild and cultivated cannabis reveals the genetic structure and adaptive selection of important traits
Abstract Background: Cannabis is an important industrial crop species whose fibre, seeds, flowers and leaves are widely used by humans.…
Comprehensive Analysis of the Expression and Prognosis for the DREAM Complex in Human Cancers
Abstract The DREAM complex is an evolutionarily conserved cell cycle regulating multi-protein complex. In addition to playing an essential function…
Tumor suppressor genes and allele-specific expression: mechanisms and significance
Abstract Recent findings indicate that allele-specific expression (ASE) at specific cancer driver gene loci may be of importance in onset/progression…