Pan-Cancer Analysis of the Prognostic and Immunological Role of ECT2: A Promising Target for Survival and Immunotherapy

Abstract Objectives: The aim of this study is to investigate the role of epithelial cell transforming sequence 2 (ECT2) as a pan-cancer biomarker and to assess its potential as an immune-related target for cancer immunotherapy. Methods: We conducted a comprehensive analysis of ECT2 expression across 44 tumor types using large-scale transcriptomic datasets from The Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression (GTEx) project. Pan-cancer Cox regression analyses were performed to evaluate the correlation between ECT2 expression and patient survival