Absence of an embryonic stem cell DNA methylation signature in human cancer
Abstract Background: Differentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory…
Lucas A. Salas
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
Abstract Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this…
Integrative epigenetic and genetic pan-cancer somatic alteration portraits
Abstract Genetic and epigenetic alterations are required for carcinogenesis and the mutation burden across tumor types has been investigated. Here,…