Structural insights into the complex of oncogenic KRas4BG12V and Rgl2, a RalA/B activator
Abstract The work reports the KRas4BG12V oncogenic mutation alters the binding kinetics with Rgl2, a RalA/B activator, and the V12…
Louise Fairall
Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting
Abstract Recent proteomic studies have identified a novel histone deacetylase complex that is upregulated during mitosis and is associated with…