RNF115 aggravates tumor progression through regulation of CDK10 degradation in thyroid carcinoma
Abstract Background: RING Finger Protein 115 (RNF115), a notable E3 ligase, is known to modulate tumorigenesis and metastasis. In our…
Longwei Guo
Identification of the H3K36me3 reader LEDGF/p75 in the pancancer landscape and functional exploration in clear cell renal cell carcinoma
Abstract Lens epithelium-derived growth factor (LEDGF/p75) is a reader of epigenetic marks and a potential target for therapeutic intervention. Its…
Comprehensive analysis of the prognostic impact and immune implication of KIAA1429 in lung adenocarcinoma
Abstract Background: Lung adenocarcinoma (LUAD) is the most common lung cancer worldwide. N6‐methyladenosine (m6A) methylation is a messenger RNA (mRNA)…
Global variation in anastomosis and end colostomy formation following left‐sided colorectal resection
Abstract Background: End colostomy rates following colorectal resection vary across institutions in high‐income settings, being influenced by patient, disease, surgeon…
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study
Abstract Background: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability…