Lakshmi Changolkar

January 1, 2021

In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics

Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00401-020-02253-4. Article type: Research Article Keywords: tauopathy, tau spreading,…

December 11, 2019

Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

Abstract The pathogenesis of glial tau pathology is unknown. This study shows glial tau pathology can propagate in the absence…

March 4, 2019

Detection of Alzheimer’s disease (AD) specific tau pathology with conformation-selective anti-tau monoclonal antibody in co-morbid frontotemporal lobar degeneration-tau (FTLD-tau)

Abstract Pathological tau aggregates in Alzheimer’s disease (AD) and frontotemporal lobar degeneration-tau (FTLD-tau) adopt distinct conformations differentiated by the AD-tau…