Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00401-021-02318-y. Article type: Research Article Keywords: Tau, Immunotherapy, Gosuranemab,…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00401-020-02253-4. Article type: Research Article Keywords: tauopathy, tau spreading,…
Abstract The pathogenesis of glial tau pathology is unknown. This study shows glial tau pathology can propagate in the absence…
Abstract Pathological tau aggregates in Alzheimer’s disease (AD) and frontotemporal lobar degeneration-tau (FTLD-tau) adopt distinct conformations differentiated by the AD-tau…
Abstract Corticobasal degeneration (CBD) is a neurodegenerative disorder affecting movement and cognition, definitively diagnosed only at autopsy. Here, we conduct…