Comprehensive analysis of BIRC5: from pan-cancer analysis to experimental validation
Abstract Background: Baculoviral inhibitor of apoptosis protein repeat-containing protein 5 (BIRC5), also known as survivin, belongs to the inhibitor of…
Jiaxin Yang
WD repeat domain 43 as a new predictive indicator and its connection with tumor immune cell infiltration in pan-cancer
Abstract Background: WD repeat domain 43 (WDR43) is a protein component that encodes WD-repeats and is involved in ribosome biogenesis.…
Structure-based identification of a G protein–biased allosteric modulator of cannabinoid receptor CB1
Abstract The opioid crisis and widespread demand for pain management have intensified the search for nonopioid analgesics, placing the CB1…
Prognostic value and immunological role of PD-L1 gene in pan-cancer
Abstract Objective: PD-L1, a target of immune checkpoint blockade, has been proven to take the role of an oncogene in…
Multiple machine-learning tools identifying prognostic biomarkers for acute Myeloid Leukemia
Abstract Background: Acute Myeloid Leukemia (AML) generally has a relatively low survival rate after treatment. There is an urgent need…
Comprehensive analysis of PILRΑ’s association with the prognosis, tumor immune infiltration, and immunotherapy in pan-cancer
Abstract Paired immunoglobulin-like type 2 receptor alpha (PILRA) plays a vital role in regulating broad immune responses. However, the roles…
Pan-cancer analysis of the PDE4DIP gene with potential prognostic and immunotherapeutic values in multiple cancers including acute myeloid leukemia
Abstract Phosphodiesterase 4D interacting protein (PDE4DIP) interacts with cAMP-specific phosphodiesterase 4D and its abnormal expression promotes the development of hematological…
Prognostic value and immunological role of FOXM1 in human solid tumors
Abstract FOXM1 acts as an oncogenic transcription factor and is involved in multiple hallmarks of human malignancies. Recent studies have…
Stenting techniques for coronary bifurcation disease: a systematic review and network meta-analysis demonstrates superiority of double-kissing crush in complex lesions
Abstract Objective: This study was aimed to compare different stenting techniques for coronary bifurcation disease (CBD). Background: Percutaneous coronary intervention…
Acceleration of wound healing in acute full-thickness skin wounds using a collagen-binding peptide with an affinity for MSCs
Abstract Mesenchymal stem cells (MSCs) have been accepted as a promising cell source in tissue repair and regeneration. However, the…