Jason Huse

July 11, 2022

JMJD8 Is an M2 Macrophage Biomarker, and It Associates With DNA Damage Repair to Facilitate Stemness Maintenance, Chemoresistance, and Immunosuppression in Pan-Cancer

Abstract Background: JMJD8 has recently been identified as a cancer-related gene, but current studies provide limited information. We aimed to…

September 21, 2020

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Abstract The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome…

February 5, 2020

Comprehensive molecular characterization of mitochondrial genomes in human cancers

Abstract Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome…

February 5, 2020

Divergent mutational processes distinguish hypoxic and normoxic tumours

Abstract Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular…

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