Strategy advancements in placental pharmacokinetics: from in vitro experiments to in silico prediction
Abstract Background: The placental barrier is a critical interface that regulates drug transport between maternal and fetal circulation and is…
Fei Wang
Cannabidiol-induced crosstalk of apoptosis and macroautophagy in colorectal cancer cells involves p53 and Hsp70
Abstract Although it has been established that cannabidiol (CBD), the major non-psychoactive constituent of cannabis, exerts antitumoral activities, the exact…
Repurposing Cannabidiol as a Potential Drug Candidate for Anti-Tumor Therapies
Abstract In recent years, evidence has accumulated that cannabinoids—especially the non-psychoactive compound, cannabidiol (CBD)—possess promising medical and pharmacological activities that…
Enzymatic properties of Thermoanaerobacterium thermosaccharolyticum β-glucosidase fused to Clostridium cellulovorans cellulose binding domain and its application in hydrolysis of microcrystalline cellulose
Abstract Background: The complete degradation of the cellulose requires the synergistic action of endo-β-glucanase, exo-β-glucanase, and β-glucosidase. But endo-β-glucanase and…