Molecular Signature Expands the Landscape of Driver Negative Thyroid Cancers
Abstract Simple Summary: Thyroid cancer is the most common endocrine malignancy. However, the cytological diagnosis of certain malignant thyroid tumors…
Eunjung Alice Lee
Evidence of Cooperation between Hippo Pathway and RAS Mutation in Thyroid Carcinomas
Abstract Simple Summary: RAS mutations have been reported in a wide range of thyroid cancer histological types, from benign to…
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Abstract The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome…
Comprehensive molecular characterization of mitochondrial genomes in human cancers
Abstract Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome…
Divergent mutational processes distinguish hypoxic and normoxic tumours
Abstract Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular…