Developmental Deconvolution for Classification of Cancer Origin
Abstract An artificial intelligence classifier trained to distinguish the developmental profiles of different tumor types is applied to cancers of…
Enrico Moiso
Tumors carrying BRAF-mutations over-express NAMPT that is genetically amplified and possesses oncogenic properties
Abstract Background: Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in nicotinamide adenine dinucleotide (NAD) biosynthesis, is up-regulated in several cancers, including…