Metabolic Responses of Melanocytes and Melanoma Cells to UVA Radiation and Phytocannabinoids Exposure
Abstract Ultraviolet A (UVA) radiation disrupts the redox balance of melanocytes and may lead to the development of melanoma, highlighting…
Elżbieta Skrzydlewska
Proteomic Analysis of the Metabolic Response of UVA-Exposed Melanocytes Following Co-Treatment with Cannabigerol and 3-O-Ethylascorbic Acid
Abstract The aim of this study was to analyze the effect of concomitant use of cannabigerol (CBG) and 3-O-ethylascorbic acid…
Natural protection against oxidative stress in human skin melanocytes
Abstract Human skin plays a crucial role in protecting the body against environmental stressors. The skin cells involved in photoprotection…
Proteomic analysis of the combined effects of cannabigerol and 3-O-ethyl ascorbic acid on kinase-dependent signalling in UVB-irradiated human keratinocytes
Abstract Oxidative stress induced by medium-wavelength ultraviolet radiation (UVB) is one of the most dangerous environmental stressors for the skin.…
3-O-Ethyl Ascorbic Acid and Cannabigerol in Modulating the Phospholipid Metabolism of Keratinocytes
Abstract Phospholipids and their metabolites play an important role in maintaining the membrane integrity and the metabolic functions of keratinocytes…
Modulation of Redox and Inflammatory Signaling in Human Skin Cells Using Phytocannabinoids Applied after UVA Irradiation: In Vitro Studies
Abstract UVA exposure disturbs the metabolism of skin cells, often inducing oxidative stress and inflammation. Therefore, there is a need…
Differences in the phospholipid profile of melanocytes and melanoma cells irradiated with UVA and treated with cannabigerol and cannabidiol
Abstract UV radiation inducing mutations in melanocytes might cause melanoma. As changes in lipid composition and metabolism are associated with…
Cannabidiol and Cannabigerol Modify the Composition and Physicochemical Properties of Keratinocyte Membranes Exposed to UVA
Abstract The action of UVA radiation (both that derived from solar radiation and that used in the treatment of skin…
Effects of combined cannabidiol (CBD) and hops (Humulus lupulus) terpene extract treatment on RAW 264.7 macrophage viability and inflammatory markers
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s13659-023-00382-3. Article type: Research Article Keywords: CBD, Terpenes, Cannabinoids,…
Protein adducts with lipid peroxidation products in patients with psoriasis
Abstract Psoriasis, one of the most frequent immune-mediated skin diseases, is manifested by numerous psoriatic lessons on the skin caused…