Renal Protection of HWL‐088and ZLY‐032, Two Dual GPR40/PPARδ Agonists, in Adenine‐Induced Renal Fibrosis Model
Abstract This research examined the potential of novel GPR40/PPARδ dual agonists, HWL‐088 and ZLY‐032, to protect the kidneys in a…
Dongbo Xue
RPN1: a pan-cancer biomarker and disulfidptosis regulator
Abstract Background: Elevated expression of SLC7A11, in conjunction with glucose deprivation, has revealed disulfidptosis as an emerging cell death modality.…
Tissue of origin prediction for cancer of unknown primary using a targeted methylation sequencing panel
Abstract Rationale: Cancer of unknown primary (CUP) is a group of rare malignancies with poor prognosis and unidentifiable tissue-of-origin. Distinct…
Cannabinoid Biosynthesis Using Noncanonical Cannabinoid Synthases
Abstract We report enzymes from the berberine bridge enzyme (BBE) superfamily that catalyze the oxidative cyclization of the monoterpene moiety…
Is preoperative MRCP necessary for patients with gallstones? An analysis of the factors related to missed diagnosis of choledocholithiasis by preoperative ultrasound
Abstract Background: The diagnosis of associated choledocholithiasis prior to cholecystectomy for patients with gallstones is important for the surgical decision…