Cannabinoids and opioid consumption in cancer pain: a systematic review and meta-analysis
Abstract Background: Opioids are the mainstay of cancer-related pain management but are limited by adverse effects and clinical complexity. Cannabinoids…
Cristina-Elena Dobre
Navigating dose-effect complexities and challenges in cannabinoid therapy for aging-related neurobiological changes
Abstract Growing evidence shows that brain aging is a time-dependent process, with very complex underlying mechanisms at molecular and cellular…
Evaluation of long-term safety profile of an EU-GMP certified Cannabis sativa L. strain in a naturally aging preclinical model
Abstract Aging is characterized in part by chronic, low-grade inflammation, a major driver of cognitive decline, metabolic imbalance and organ…