Abstract Background and Objectives: Chronic inflammation of bone tissue often results in bone defects and hazards to tissue repair and…
Keywords: Tumor mutational burden (TMB), Molecular alterations, Differential expression, Signaling pathway, Immunology, Survival Authors: Lin Li, Long Bai, Huan Lin,…
Keywords: Spliceosome pathway, Pan-cancer, Anti-tumor immunity, Cancer immunotherapy, Drug response, Genomic instability Authors: Zuobing Chen, Canping Chen, Lin Li, Tianfang…
Abstract The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome…
Abstract Intratumor heterogeneity (ITH) is a biomarker of tumor progression, metastasis, and immune evasion. Previous studies evaluated ITH mostly based…
Abstract The diamine monomer, 9,9-bis[4-(4-amino-3-hydroxylphenoxy)phenyl] fluorene (bis-AHPPF) was successfully synthesized according to our modified method. A series of hydroxyl-containing poly(ether-imide)s…
Abstract Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular…
Abstract Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome…