Down-regulation of interleukin-2 predicts poor prognosis and associated with immune escape in lung adenocarcinoma
Abstract Background and Objective: Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer and has a poor prognosis.…
Abstract Background and Objective: Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer and has a poor prognosis.…
Abstract Background: Testicular cancer severely affects male health, so finding effective diagnosis and prognostic indicators and exploring its pathogenesis are…
Abstract Background: The family with sequence similarity 20-member C (Fam20C) kinase plays important roles in physiopathological process and is responsible…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00401-020-02253-4. Article type: Research Article Keywords: tauopathy, tau spreading,…
Abstract The pathogenesis of glial tau pathology is unknown. This study shows glial tau pathology can propagate in the absence…
Abstract RNA-binding proteins (RBPs) are key regulators of posttranscriptional processes such as RNA maturation, localization, turnover and translation. Despite their…
Abstract Hyperglycemia-induced oxidative stress and fibrosis play a crucial role in the development of diabetic cardiomyopathy (DCM). Tetrahydrocurcumin (THC), a…