HELQ as a DNA helicase: Its novel role in normal cell function and tumorigenesis (Review)
Abstract Helicase POLQ-like (HELQ or Hel308), is a highly conserved, 3′-5′ superfamily II DNA helicase that contributes to diverse DNA…
Review Article
The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses
Abstract Cannabis is well established to impact affective states, emotion and perceptual processing, primarily through its interactions with the endocannabinoid…
Imaging and Genetic Tools for the Investigation of the Endocannabinoid System in the CNS
Abstract As central nervous system (CNS)-related disorders present an increasing cause of global morbidity, mortality, and high pressure on our…
Long-term efficacy and adverse effects of cannabidiol in adjuvant treatment of drug-resistant epilepsy: a systematic review and meta-analysis
Abstract Background: Epilepsy is one of the most common chronic brain diseases. Almost one-third of patients have drug-resistant epilepsy (DRE).…
Anxiety Modulation by Cannabinoids—The Role of Stress Responses and Coping
Abstract Endocannabinoids were implicated in a variety of pathological conditions including anxiety and are considered promising new targets for anxiolytic…
Cannabis and Rheumatoid Arthritis: A Scoping Review Evaluating the Benefits, Risks, and Future Research Directions
Abstract Rheumatoid diseases, including rheumatoid arthritis, osteoarthritis, and fibromyalgia, are characterized by progressive inflammation in the musculoskeletal system, predominantly affecting…
Neuro-Gastro-Cannabinology: A Novel Paradigm for Regulating Mood and Digestive Health
Abstract The maintenance of homeostasis in the gastrointestinal (GI) tract is ensured by the presence of the endocannabinoid system (ECS),…
Imaging plant metabolism in situ
Abstract Mass spectrometry imaging (MSI) has emerged as an invaluable analytical technique for investigating the spatial distribution of molecules within…
Supporting gut health with medicinal cannabis in people with advanced cancer: potential benefits and challenges
Abstract The side effects of cancer therapy continue to cause significant health and cost burden to the patient, their friends…
The Use of Intraoperative Cholangiography During Cholecystectomy: A Systematic Review
Abstract Cholecystectomy is a widespread surgical procedure for gallbladder diseases. Evolving techniques and technologies, such as intraoperative cholangiography (IOC), enhance…