Cannabidiol as a possible treatment for endometriosis through suppression of inflammation and angiogenesis
Abstract Background: Endometriosis is associated with a wide variety of signs and symptoms and can lead to infertility, embryo death,…
Review Article
Therapeutic Application of Modulators of Endogenous Cannabinoid System in Parkinson’s Disease
Abstract The endogenous cannabinoid system (ECS) of the brain plays an important role in the molecular pathogenesis of Parkinson’s disease…
Enhancing Withanolide Production in the Withania Species: Advances in In Vitro Culture and Synthetic Biology Approaches
Abstract Withanolides are naturally occurring steroidal lactones found in certain species of the Withania genus, especially Withania somnifera (commonly known…
From Classical to Alternative Pathways of 2-Arachidonoylglycerol Synthesis: AlterAGs at the Crossroad of Endocannabinoid and Lysophospholipid Signaling
Abstract 2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full agonist at both CB1 and CB2 cannabinoid…
Clinical Benefits and Safety of Medical Cannabis Products: A Narrative Review on Natural Extracts
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s40122-024-00643-0. Article type: Review Article Keywords: Cannabinoids, Cannabidiol, Tetrahydrocannabinol,…
Review of the Patient Burden and Therapeutic Landscape of Irritable Bowel Syndrome with Constipation in the United States
Abstract Irritable bowel syndrome (IBS) is a common disorder of the gut–brain axis. IBS with constipation (IBS-C) accounts for approximately…
Systematic review and meta-analysis on the effects of chronic peri-adolescent cannabinoid exposure on schizophrenia-like behaviour in rodents
Abstract Background: The link between cannabis use and schizophrenia is well-established in epidemiological studies, especially among adolescents with early-onset use.…
Impact of Lipids on Insulin Resistance: Insights from Human and Animal Studies
Abstract Insulin resistance (IR) is a complex pathological condition central to metabolic diseases such as type 2 diabetes mellitus (T2DM),…
Evaluation of Cannabis-Related Product Use Among Patients With Hidradenitis Suppurativa: A Narrative Review
Abstract The use of cannabis and cannabis-related products among patients with hidradenitis suppurativa (HS) is increasing globally. Given the potential…
The Potential of Metabolomics to Find Proper Biomarkers for Addressing the Neuroprotective Efficacy of Drugs Aimed at Delaying Parkinson’s and Alzheimer’s Disease Progression
Abstract The first objective is to highlight the lack of tools to measure whether a given intervention affords neuroprotection in…