Cannabinoids and Genetic Epilepsy Models: A Review with Focus on CDKL5 Deficiency Disorder
Abstract Pediatric genetic epilepsies, such as CDKL5 Deficiency Disorder (CDD), are severely debilitating, with early-onset seizures occurring more than ten…
Review Article
Comparative efficacy and safety of different pharmacological therapies to medication overuse headache: a network meta-analysis
Abstract Background: Controversy exists whether prophylactic drugs are necessary in the treatment of medication overuse headache (MOH). Objectives: To determine…
Updated Risk Assessment of Cannabidiol in Foods Based on Benchmark Dose–Response Modeling
Abstract Cannabidiol (CBD), a non-psychotropic main component of the Cannabis plant, has been approved as a drug in the European…
The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review
Abstract Cannabidiol (CBD) is a non-psychotropic cannabinoid with multiple pharmacological properties. Cannabidiol has attracted growing attention in the cosmetic industry,…
Medicinal plants and plant-based traditional medicine: Alternative treatments for depression and their potential mechanisms of action
Abstract Background: Clinical depression is a serious public health issue that affects 4.7 % of the world’s population and can…
GPCRs: emerging targets for novel T cell immune checkpoint therapy
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00262-024-03801-7. Article type: Review Article Keywords: GPCRs, Immune checkpoint…
Illuminating Cannabis sativa L.: The Power of Light in Enhancing C. sativa Growth and Secondary Metabolite Production
Abstract Light is crucial for higher plants, driving photosynthesis and serving as a powerful sensory signal that profoundly modulates growth,…
The Evolution of Illicit-Drug Detection: From Conventional Approaches to Cutting-Edge Immunosensors—A Comprehensive Review
Abstract The increasing use of illicit drugs has become a major global concern. Illicit drugs interact with the brain and…
Harnessing Cannabis sativa Oil for Enhanced Skin Wound Healing: The Role of Reactive Oxygen Species Regulation
Abstract Cannabis sativa emerges as a noteworthy candidate for its medicinal potential, particularly in wound healing. This review article explores…
A Systematic Review of Delta-9-Tetrahydrocannabinol (∆9-THC) in Astrocytic Markers
Abstract Background: Astrocytic reactivity in substance use disorders (SUDs) has been extensively studied, yet the molecular effect of delta-9-tetrahydrocannabinol (∆9-THC,…