Is Endoscopic Papillary Large Balloon Dilation Safe for Treating Large CBD Stones?
Abstract In recent years, endoscopic papillary large balloon dilation (EPLBD) with endoscopic sphincterotomy (EST) has been shown to be an…
Review Article
Tackling the Pharmaceutical Frontier: Regulation of Cannabinoid-Based Medicines in Postwar Japan
Abstract Background: The valley of death, which refers to the gap due to the lack of support for the translation…
Allosteric Modulators of the CB1 Cannabinoid Receptor: A Structural Update Review
Abstract In 2005, the first evidence of an allosteric binding site at the CB1R was provided by the identification of…
Cellular Mechanisms of Action of Drug Abuse on Olfactory Neurons
Abstract Cannabinoids (Δ9-tetrahydrocannabinol) are the active ingredient of marijuana (cannabis) which is the most commonly abused illicit drug in the…
To Act or Not to Act: Endocannabinoid/Dopamine Interactions in Decision-Making
Abstract Decision-making is an ethologically adaptive construct that is impaired in multiple psychiatric disorders. Activity within the mesocorticolimbic dopamine system…
Oxyradical Stress, Endocannabinoids, and Atherosclerosis
Abstract Atherosclerosis is responsible for most cardiovascular disease (CVD) and is caused by several factors including hypertension, hypercholesterolemia, and chronic…
Zellweger spectrum disorders: clinical overview and management approach
Abstract Zellweger spectrum disorders (ZSDs) represent the major subgroup within the peroxisomal biogenesis disorders caused by defects in PEX genes.…
Oculo-Visual Dysfunction in Parkinson’s Disease
Abstract This review describes the oculo-visual problems likely to be encountered in Parkinson’s disease (PD) with special reference to three…
Hypothalamic control of brown adipose tissue thermogenesis
Abstract It has long been known, in large part from animal studies, that the control of brown adipose tissue (BAT)…
Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling
Abstract One of the unique features of prenatal alcohol exposure in humans is impaired cognitive and behavioral function resulting from…