HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads
Abstract As a popular psychostimulant, methamphetamine (METH) use leads to long-lasting, strong euphoric effects. While METH abuse is common in…
Review Article
Pathophysiology of anorexia in the cancer cachexia syndrome
Abstract Anorexia is commonly present in persons with cancer and a major component of cancer cachexia. There are multiple causes…
Antioxidant therapy for treatment of inflammatory bowel disease: Does it work?
Abstract Oxidative stress (OS) is considered as one of the etiologic factors involved in several signals and symptoms of inflammatory…
Emerging drugs of abuse: current perspectives on synthetic cannabinoids
Abstract New psychoactive drugs that have appeared over the last decade are typically dominated by cathinones and synthetic cannabinoids (SCs).…
Current and Future Prospects for Epigenetic Biomarkers of Substance Use Disorders
Abstract Substance abuse has an enormous impact on economic and quality of life measures throughout the world. In more developed…
Plant derived substances with anti-cancer activity: from folklore to practice
Abstract Plants have had an essential role in the folklore of ancient cultures. In addition to the use as food…
Cannabinoid Ligands and Alcohol Addiction: A Promising Therapeutic Tool or a Humbug?
Abstract The vast therapeutic potential of cannabinoids of both synthetic and plant-derived origins currently makes these compounds the focus of…
High Times for Painful Blues: The Endocannabinoid System in Pain-Depression Comorbidity
Abstract Depression and pain are two of the most debilitating disorders worldwide and have an estimated cooccurrence of up to…
Marijuana for Glaucoma: A Recipe for Disaster or Treatment?
Abstract Marijuana has been shown to lower intraocular pressure (IOP) but with limited duration of action and numerous adverse effects.…
U.S. Policy Responses to Calls for the Medical Use of Cannabis
Abstract This paper discusses the evolution of U.S. policy responses to calls to allow patients to use cannabis for medical…