Systematic Review of Pharmacological Properties of the Oligodendrocyte Lineage
Abstract Oligodendrogenesis and oligodendrocyte precursor maturation are essential processes during the course of central nervous system development, and lead to…
Review Article
Endocannabinoids as Guardians of Metastasis
Abstract Endocannabinoids including anandamide and 2-arachidonoylglycerol are involved in cancer pathophysiology in several ways, including tumor growth and progression, peritumoral…
Clinical utility of dronabinol in the treatment of weight loss associated with HIV and AIDS
Abstract Since the beginning of the HIV/AIDS epidemic, weight loss has been a common complaint for patients. The use of…
Fischer 344 and Lewis Rat Strains as a Model of Genetic Vulnerability to Drug Addiction
Abstract Today it is well acknowledged that both nature and nurture play important roles in the genesis of psychopathologies, including…
Cannabis sativa: The Plant of the Thousand and One Molecules
Abstract Cannabis sativa L. is an important herbaceous species originating from Central Asia, which has been used in folk medicine…
Endocannabinoids in the Gut
Abstract Cannabis has been used medicinally for centuries to treat a variety of disorders, including those associated with the gastrointestinal…
Metabolic Interplay between Peroxisomes and Other Subcellular Organelles Including Mitochondria and the Endoplasmic Reticulum
Abstract Peroxisomes are unique subcellular organelles which play an indispensable role in several key metabolic pathways which include: (1.) etherphospholipid…
Microglial Cells as a Link between Cannabinoids and the Immune Hypothesis of Psychiatric Disorders
Abstract Psychiatric disorders are one of the leading causes of disability worldwide. Although several therapeutic options are available, the exact…
Modulation of Fear Extinction by Stress, Stress Hormones and Estradiol: A Review
Abstract Fear acquisition and extinction are valid models for the etiology and treatment of anxiety, trauma- and stressor-related disorders. These…
Neuropsychological Consequences of Chronic Drug Use: Relevance to Treatment Approaches
Abstract Heavy use of drugs impacts of the daily activities of individuals in these activities. Several groups of investigators have…