Endocannabinoid system in cardiovascular disorders – new pharmacotherapeutic opportunities
Abstract The long history of Cannabis sativa had its development stimulated and oriented for medicine after the discovery and chemical…
Review Article
Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives
Abstract Many synthetic drugs reported to be used for the treatment of inflammatory disorders are of least interest now a…
Topical preparations for pain relief: efficacy and patient adherence
Abstract There has been an increasing focus on development of new routes of drug administration to provide tailored treatments for…
Cannabinoids and Reproduction: A Lasting and Intriguing History
Abstract Starting from an historical overview of lasting Cannabis use over the centuries, we will focus on a description of…
Adolescent Brain Development and the Risk for Alcohol and Other Drug Problems
Abstract Dynamic changes in neurochemistry, fiber architecture, and tissue composition occur in the adolescent brain. The course of these maturational…
Endocannabinoids and Schizophrenia
Abstract The endocannabinoids anandamide and 2-arachydonoylglycerol (2-AG) are lipids naturally derived from membrane precursors which bind cannabinoid receptors (CB1, CB2).…
Tissue Engineering of Cartilage; Can Cannabinoids Help?
Abstract This review discusses the role of the cannabinoid system in cartilage tissue and endeavors to establish if targeting the…
Investigational pharmacology for low back pain
Abstract Study design: Review and reinterpretation of existing literature. Objective: This review article summarizes the anatomy and pathogenesis of disease…
Mechanisms of Broad-Spectrum Antiemetic Efficacy of Cannabinoids against Chemotherapy-Induced Acute and Delayed Vomiting
Abstract Chemotherapy-induced nausea and vomiting (CINV) is a complex pathophysiological condition and consists of two phases. The conventional CINV neurotransmitter…
From Fertilisation to Implantation in Mammalian Pregnancy—Modulation of Early Human Reproduction by the Endocannabinoid System
Abstract There is an increasing recognition that the endocannabinoid system is the crucial cytokine-hormone system regulating early human pregnancy. The…