Two dimensional NMR spectroscopic approaches for exploring plant metabolome: A review
Keywords: Nuclear magnetic resonance (NMR), Phytomedicines, Drug discovery, 2D NMR, Metabolomics, Chemometrics Authors: Engy A. Mahrous, Mohamed A. Farag License:…
Review Article
Legalizing Cannabis: A physician’s primer on the pulmonary effects of marijuana
Abstract Habitual smoking of marijuana is associated with multiple respiratory symptoms such as cough, sputum production, and wheezing .These symptoms…
Palonosetron in the management of chemotherapy-induced nausea and vomiting in patients receiving multiple-day chemotherapy
Abstract Prevention of chemotherapy-induced nausea and vomiting (CINV) is a key component of treatment for patients with cancer. Guidelines are…
Endocannabinoid-Dependent Modulation of Phasic Dopamine Signaling Encodes External and Internal Reward-Predictive Cues
Abstract The mesolimbic dopamine (DA) system plays an integral role in incentive motivation and reward seeking and a growing body…
Control of synaptic function by endocannabinoid-mediated retrograde signaling
Abstract Since the first reports in 2001, great advances have been made towards the understanding of endocannabinoid-mediated synaptic modulation. Electrophysiological…
Cannabinoid Regulation of Brain Reward Processing with an Emphasis on the Role of CB1 Receptors: A Step Back into the Future
Abstract Over the last decades, the endocannabinoid system has been implicated in a large variety of functions, including a crucial…
Cannabinoids as therapeutic agents in cancer: current status and future implications
Abstract The pharmacological importance of cannabinoids has been in study for several years. Cannabinoids comprise of (a) the active compounds…
The Role of Cannabinoid Transmission in Emotional Memory Formation: Implications for Addiction and Schizophrenia
Abstract Emerging evidence from both basic and clinical research demonstrates an important role for endocannabinoid (ECB) signaling in the processing…
Transient Receptor Potential Channels as Targets for Phytochemicals
Abstract To date, 28 mammalian transient receptor potential (TRP) channels have been cloned and characterized. They are grouped into six…
TRP Channel Cannabinoid Receptors in Skin Sensation, Homeostasis, and Inflammation
Abstract In the skin, cannabinoid lipids, whether of endogenous or exogenous origin, are capable of regulating numerous sensory, homeostatic, and…