Clinical Development of Targeted Fragile X Syndrome Treatments: An Industry Perspective
Abstract Fragile X syndrome (FXS) is the leading known cause of inherited intellectual disability and autism spectrum disorder. It is…
Review Article
Crosstalk Between Nitric Oxide and Endocannabinoid Signaling Pathways in Normal and Pathological Placentation
Abstract Endocannabinoids are a group of endogenous lipid mediators that act as ligands of cannabinoid and vanilloid receptors, activating multiple…
Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer
Abstract In the last decades, a lot of attention has been paid to the compounds present in medicinal Cannabis sativa…
A Review of Herbal Therapy in Multiple Sclerosis
Abstract Multiple sclerosis is a complex autoimmune disorder which characterized by demyelination and axonal loss in the central nervous system…
The Effects of Substance Abuse on Blood Glucose Parameters in Patients with Diabetes: A Systematic Review and Meta-Analysis
Abstract Background: People who abuse substances are at increased risk of metabolic syndrome and diabetes resulting partly from increased cell…
Management of nightmares in patients with posttraumatic stress disorder: current perspectives
Abstract Nightmares are considered the hallmark of posttraumatic stress disorder (PTSD). Although the characteristics of these distressing dreams may vary…
Cannabinoids and Pain: New Insights From Old Molecules
Abstract Cannabis has been used for medicinal purposes for thousands of years. The prohibition of cannabis in the middle of…
Cannabis, Cannabinoids, and the Endocannabinoid System—Is there Therapeutic Potential for Inflammatory Bowel Disease?
Abstract Cannabis sativa and its extracts have been used for centuries, both medicinally and recreationally. There is accumulating evidence that…
Herbs and Spices in the Treatment of Functional Gastrointestinal Disorders: A Review of Clinical Trials
Abstract More than fifty percent of all new patient visits to pediatric gastroenterology clinics consult for functional abdominal pain disorders…
Potential for endocannabinoid system modulation in ocular pain and inflammation: filling the gaps in current pharmacological options
Abstract Challenges in the management of ocular pain are an underappreciated topic. Currently available therapeutics lack both efficacy and clear…