Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease
Abstract The identification and cloning of the two major cannabinoid (CB1 and CB2) receptors together with the discovery of their…
Review Article
Medical treatment of dystonia
Abstract Therapeutic strategies in dystonia have evolved considerably in the past few decades. Three major treatment modalities include oral medications,…
Targeting calcium signaling in cancer therapy
Abstract The intracellular calcium ions (Ca2+) act as second messenger to regulate gene transcription, cell proliferation, migration and death. Accumulating…
Endocannabinoid System: the Direct and Indirect Involvement in the Memory and Learning Processes—a Short Review
Abstract The endocannabinoid system via cannabinoid (CB: CB1 and CB2) receptors and their endogenous ligands is directly and indirectly involved…
Can cannabinoids be a potential therapeutic tool in amyotrophic lateral sclerosis?
Abstract Amyotrophic lateral sclerosis (ALS) is the most common degenerative disease of the motor neuron system. Over the last years,…
Cannabidiol as a Potential New Type of an Antipsychotic. A Critical Review of the Evidence
Abstract There is urgent need for the development of mechanistically different and less side-effect prone antipsychotic compounds. The endocannabinoid system…
Effect of cannabis smoking on lung function and respiratory symptoms: a structured literature review
Abstract As cannabis use increases, physicians need to be familiar with the effects of both cannabis and tobacco on the…
Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents
Abstract Cancer is the second leading cause of death in the United States with 1.7 million new cases estimated to…
The Name of Cannabis: A Short Guide for Nonbotanists
Abstract The genus Cannabis (Family Cannabaceae) is probably indigenous to wet habitats of Asiatic continent. The long coexistence between mankind…
Medical cannabis – the Canadian perspective
Abstract Cannabis has been widely used as a medicinal agent in Eastern medicine with earliest evidence in ancient Chinese practice…