Modulatory Effects of “Minor” Cannabinoids in an in vitro Model of Neuronal Hypersensitivity
Abstract Aim: Effective treatment for neuropathic pain remains an unmet clinical need. The therapeutic benefits of the Cannabis plant are…
Research Article
Cannabis-based extract for managing pain in dogs with osteoarthritis: efficacy and safety assessment
Abstract Introduction: Canine osteoarthritis (OA) is a prevalent disease characterized by progressive joint degeneration, pain, and impaired mobility. In older…
A novel protocol for protoplast isolation, transfection, and culture in Cannabis sativa L
Abstract Background: Protoplasts are a valuable tool for studying gene expression and applying genome editing techniques. Given the high medicinal…
Comparative effects of Berberis vulgaris extract and casein nanocapsules on the antioxidant activity and oxidative stability of selected vegetable oils
Abstract This study aimed to enhance the stability and functionality of Berberis vulgaris anthocyanins through casein-based encapsulation and to evaluate…
Cannabis Use and Glutamate across the Psychosis Spectrum: In Vivo Evidence from 7T Proton Magnetic Resonance Spectroscopy
Abstract Cannabis use is linked to elevated psychosis risk, yet the neurobiological mechanisms that couple use to symptom expression remain…
Genotype and chemotype insights of high-THC medicinal Cannabis sativa L.: the role of SSR markers in the identification of cultivars
Abstract Background: Standardized methods for distinguishing high-THC Cannabis sativa L. genotype versus chemotype of cultivars remain limited, posing challenges for…
Insights into cannabinoid receptor 2 (CB2) anterograde trafficking and pharmacological chaperoning
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00018-025-05961-w. Article type: Research Article Keywords: Receptor, cannabinoid, Cannabinoid…
Effect of Central Injection of Anandamide on LPS-Dependent Suppression of GnRH/LH Secretion in Ewes During the Follicular Phase of the Estrous Cycle
Abstract The study investigated the effects of intracerebroventricular (ICV) administration of the endocannabinoid anandamide (AEA) on suppression of gonadotropin-releasing hormone…
Protective effects of hydrocolloid nanoemulsion coatings against myofibrillar protein oxidation in frozen trout
Abstract In this study, rainbow trout filets were coated using a dipping method with a nanoemulsion derived from aloe vera…
Medical cannabis utilization in children – a study based on a nationwide cohort
Abstract Introduction: This study aimed to evaluate the utilization of medical cannabis in a pediatric population and compare short-term persistence…