Spot tests: past and present
Abstract Graphic abstract: Article type: Research Article Keywords: Spot tests, Microchemistry, Chemical microscopy, Dipstick immunoassay, ELISA, Microfluidics, µPAD, Lab-on-a-chip, Multiplexed…
Research Article
Cannabinoid control of gingival immune activation in chronically SIV-infected rhesus macaques involves modulation of the indoleamine-2,3-dioxygenase-1 pathway and salivary microbiome
Abstract Background: HIV/SIV-associated periodontal disease (gingivitis/periodontitis) (PD) represents a major comorbidity affecting people living with HIV (PLWH) on combination anti-retroviral…
Pre-exposure prophylaxis use, HIV knowledge, and internalized homonegativity among men who have sex with men in Brazil: A cross-sectional study
Abstract Background: Pre-exposure prophylaxis (PrEP) use in Brazil remains low despite free national access. We explored associations of HIV knowledge…
Disparity between Perceptual Fall Risk and Physiological Fall Risk in Older Cannabis Users: A Pilot Study
Abstract Aging is associated with cognitive decline and increased fall risk. Cognitive impairment is associated with cannabis use, which is…
Medical Cannabis Use Among Older Adults in Canada: Self-Reported Data on Types and Amount Used, and Perceived Effects
Abstract Background: Medical cannabis use is growing among older adults. In this retrospective study, we aimed to assess the characteristics…
Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats
Abstract In spite of use of cannabidiol (CBD), a non-psychoactive cannabinoid, in pediatric patients with epilepsy, preclinical studies on its…
Sex differences in acute cannabis effects revisited: Results from two randomized, controlled trials
Abstract Some evidence suggests that males and females may differ in their responses to acute cannabis effects, including subjective drug…
FUS driven circCNOT6L biogenesis in mouse and human spermatozoa supports zygote development
Abstract Circular RNA (circRNA) biogenesis requires a backsplicing reaction, promoted by inverted repeats in cis-flanking sequences and trans factors, such…
Direct healthcare costs and their relationships with age at start of drug use and current pattern of use: a cross-sectional study
Abstract BACKGROUND: It is well known that early start of drug use can lead users to psychosocial problems in adulthood,…
Cannabis sativa L. (var. indica) Exhibits Hepatoprotective Effects by Modulating Hepatic Lipid Profile and Mitigating Gluconeogenesis and Cholinergic Dysfunction in Oxidative Hepatic Injury
Abstract Cannabis sativa L. is a crop utilized globally for recreational, therapeutic, and religious purposes. Although considered as an illicit…