In vivo Evidence for Brain Region-Specific Molecular Interactions Between Cannabinoid and Orexin Receptors
Abstract The endocannabinoid and orexin neuromodulatory systems serve key roles in many of the same biological functions such as sleep,…
Research Article
Selection and validation of reference genes for normalization of qRT-PCR data to study the cannabinoid pathway genes in industrial hemp
Abstract There has been significant interest in researching the pharmaceutical applications of Industrial hemp since its legalization three years ago.…
Infodemiological Examination of Personal and Commercial Tweets About Cannabidiol: Term and Sentiment Analysis
Abstract Background: In the absence of official clinical trial information, data from social networks can be used by public health…
Novel Association between Opioid Use and Increased Risk of Retinal Vein Occlusion Using the National Institutes of Health All of Us Research Program
Abstract Purpose: To assess for risk factors for retinal vein occlusion (RVO) among participants in the National Institutes of Health…
Relationships between the Decomposition Behaviour of Renewable Fibres and Their Reinforcing Effect in Composites Processed at High Temperatures
Abstract Engineering polymers reinforced with renewable fibres (RF) are an attractive class of materials, due to their excellent mechanical performance…
Frequencies of emergency department use and hospitalization comparing patients with different types of substance or polysubstance-related disorders
Abstract Background: This study measured emergency department (ED) use and hospitalization for medical reasons among patients with substance-related disorders (SRD),…
Pharmacokinetics, Safety, and Tolerability of a Medicinal Cannabis Formulation in Patients with Chronic Non-cancer Pain on Long-Term High Dose Opioid Analgesia: A Pilot Study
Abstract Introduction: This phase I open-label study examined pharmacokinetics, safety, and tolerability of escalating doses of a novel combination cannabinoid…
Lignin–Cellulose Nanocrystals from Hemp Hurd as Light-Coloured Ultraviolet (UV) Functional Filler for Enhanced Performance of Polyvinyl Alcohol Nanocomposite Films
Abstract Lignin is a natural light-coloured ultraviolet (UV) absorber; however, conventional extraction processes usually darken its colour and could be…
Analysis of bicycle helmet damage visibility for concussion-threshold impacts
Abstract Any helmet involved in an accident should be replaced, regardless of appearance after impact. However, consumer compliance and interpretation…
Impact of Preparation of Titanium Alloys on Their Abrasive Water Jet Machining
Abstract Several titanium alloys, i.e., grade 2 Ti, Ti6Al4V and NiTi alloy, prepared by selected deformation procedures were subjected to…