Cannabis Seedlings Inherit Seed-Borne Bioactive and Anti-Fungal Endophytic Bacilli
Abstract Throughout the hundreds of millions of years of co-evolution, plants and microorganisms have established intricate symbiotic and pathogenic relationships.…
Research Article
A Review of Historical Context and Current Research on Cannabis Use in India
Abstract Background: The cultivation and use of cannabis is historically rooted in the Indian subcontinent and this rich heritage of…
Mucosal Delivery of Cannabidiol: Influence of Vehicles and Enhancers
Abstract In this study, the mucosal permeation and deposition of cannabidiol (CBD) with neat and binary vehicles were investigated. Permeation…
Antibacterial, Antibiofilm, and Antioxidant Activity of 15 Different Plant-Based Natural Compounds in Comparison with Ciprofloxacin and Gentamicin
Abstract Plant-based natural compounds (PBCs) are comparatively explored in this study to identify the most effective and safe antibacterial agent/s…
In vitro evaluation of the impact of Covid-19 therapeutic agents on the hydrolysis of the antiviral prodrug remdesivir
Abstract Remdesivir (RDV, Veklury®) is an FDA-approved prodrug for the treatment of hospitalized patients with COVID-19. Recent in vitro studies…
Cannabidiol Inhibits Inflammation Induced by Cutibacterium acnes-Derived Extracellular Vesicles via Activation of CB2 Receptor in Keratinocytes
Abstract Background: Acne is a common inflammatory skin disease, while cannabidiol (CBD) is a representative non-psychoactive phytocannabinoid which has been…
The epiphany derived from T-cell–inflamed profiles: Pan-cancer characterization of CD8A as a biomarker spanning clinical relevance, cancer prognosis, immunosuppressive environment, and treatment responses
Abstract CD8A encodes the CD8 alpha chain of αβT cells, which has been proposed as a quantifiable indicator for the…
Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia
Abstract Toll-like receptor 4 (TLR4) is a pattern-recognition receptor (PRR) that regulates the activation of immune cells, which is a…
Can cannabis kill? Characteristics of deaths following cannabis use in England (1998–2020)
Abstract Background: Cannabis is the most widely used illegal drug but is rarely considered a causal factor in death. Aims:…
Nurses’ professional values and organizational commitment
Abstract Objectives: Both professional values and organizational commitment are strongly affected by variations among individuals. Identifying personal differences and their…