Cannabidiol in Food and Food Supplements: Drug, Novel Food and Hazard Triangle
Abstract The concept of the “cannabidiol (CBD) Hazard Triangle” reflects the unique position of CBD at the intersection of three…
Research Article
Protocol to prepare inclusion complex-enhanced cannabinoid nano-micelles for behavioral pharmacology and in vivo neurophysiology in mice
Abstract Cannabinoids have significant therapeutic potential but are limited by hydrophobicity and low bioavailability. Here, we present a protocol for…
Effects of anthelmintics and gastrointestinal nematode infection intensity on growth and production performance and carcass quality in western Canadian feedlot cattle
Abstract A randomized controlled trial determined the effects of anthelmintic treatments on growth and production performance, and carcass quality in…
Endocannabinoid system modulation in bruxism: a neurobiological hypothesis and translational model of ECS-targeted intervention
Abstract Bruxism is a multifactorial motor behavior of predominantly central origin, characterized by repetitive masticatory muscle activity and associated with…
Breast milk Δ9-tetrahydrocannabinol in cannabis users during the postpartum period: correlation between breast milk, maternal urine and saliva samples during early lactation
Abstract Introduction: Cannabis use during pregnancy and the postpartum period has increased in recent years, raising clinical concerns regarding maternal…
Systematic pan-cancer analysis reveals context-dependent prognostic and immunological roles of WDR1 with divergent effects in renal and gastric cancers
Abstract Background: WD-repeat domain 1 (WDR1), a key regulator of actin cytoskeleton dynamics, has been implicated in tumor progression. However,…
Combined Administration of Cannabidiol and L-Theanine Improves Sleep-Related Outcomes in Caffeine-Induced Sleep Disturbances Mouse Model
Abstract Sleep disruption is associated with increased risks of metabolic, cardiovascular, and neuropsychiatric disorders. Cannabidiol (CBD) and L-theanine have attracted…
A γ-radiation-responsive diselenide-core micelle for on-demand delivery of cannabidiol in the mitigation of acute radiation injury
Abstract With the widespread application of nuclear energy, the associated risks of nuclear accidents and radiation leakage have increased considerably.…
Documented Nicotine, Cannabis, and Co-Use Are Associated With More Intensive Emergency Department Care for Adolescent Asthma Exacerbations
Abstract Objectives: Asthma exacerbations pose substantial risk to adolescents. We evaluated whether documented nicotine use, cannabis use, or concurrent use…
Antidepressant-like effects of cannabidiol when combined with temozolomide in adult rats
Abstract There is a need for characterizing more efficacious therapeutic strategies for glioblastoma multiforme to overcome treatment resistance to the…