Social Stigma and Discrimination Toward People With Drug Addiction: A National Survey in Korea
Abstract Objective: This study aims to understand the attitudes, stigma, and discrimination of the general adult population toward drug addiction.…
Research Article
PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice
Abstract Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that regulate gene expression. Δ9-tetrahydrocannabinol (Δ9-THC) is a PPARγ…
Long-Term Treatment with Cannabidiol-Enriched Cannabis Extract Induces Synaptic Changes in the Adolescent Rat Hippocampus
Abstract The endocannabinoid system (eCS) is widely distributed in mammalian tissues and it is classically formed by cannabinoid receptors, endogenous…
Melatonin enhances KCl salinity tolerance by maintaining K+ homeostasis in Malus hupehensis
Abstract Large amounts of potash fertilizer are often applied to apple (Malus domestica) orchards to enhance fruit quality and yields,…
Low Doses of β-Caryophyllene Reduced Clinical and Paraclinical Parameters of an Autoimmune Animal Model of Multiple Sclerosis: Investigating the Role of CB2 Receptors in Inflammation by Lymphocytes and Microglial
Abstract Multiple Sclerosis (MS) is a prevalent inflammatory disease in which the immune system plays an essential role in the…
Cannabis use among workers with work-related injuries and illnesses: results from a cross-sectional study of workers’ compensation claimants in Ontario, Canada
Abstract Objectives: Little is known about how workers use cannabis following a work-related injury/illness, including whether they receive clinical guidance.…
Hippocampal differential expression underlying the neuroprotective effect of delta-9-tetrahydrocannabinol microdose on old mice
Abstract Delta-9-tetrahydrocannabinol (THC) is the primary psychoactive compound of the cannabis plant and an exogenous ligand of the endocannabinoid system.…
Novel Molecular Consortia of Cannabidiol with Nonsteroidal Anti-Inflammatory Drugs Inhibit Emerging Coronaviruses’ Entry
Abstract The COVID-19 pandemic provoked a global health crisis and highlighted the need for new therapeutic strategies. In this study,…
MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control
Abstract Despite the clinical availability of over 30 antiseizure medications, around 30% of people with epilepsy do not achieve seizure…
Impulsivity and Alcohol Use during Pregnancy and Postpartum: Insights from Novel Methodological Approaches within the Context of the COVID-19 Pandemic
Abstract Impaired emotion regulation and impulsivity have been linked to substance use. This study evaluated the association between emotion regulation…