Intensity of Psychoactive Substance Use Affects the Occurrence of Prodromal Symptoms of Psychosis
Abstract Background: Psychosis is defined as a series of symptoms that impair the mind and lead to a kind of…
Research Article
The role of stigma in cannabis use disclosure: an exploratory study
Abstract Background: Although cannabis use incidence, societal acceptance, and legislation all trend positively, cannabis remains federally illegal in the USA.…
Dysfunction in endocannabinoids, palmitoylethanolamide, and degradation of tryptophan into kynurenine in individuals with depressive symptoms
Abstract Background: The endocannabinoid (eCB) system and the serotonin (5-HT) are both implicated in the severity of the depression. 5-HT…
The trend of poisonings before and after the COVID-19 pandemic
Abstract The COVID-19 pandemic has substantially affected people and healthcare systems. One of the main challenges was the reduction and…
Quantification of Δ9-tetrahydrocannabinol in urine as a marker of cannabis abuse
Abstract Background & objectives: Cannabis use has long been associated with celebration and hospitality, although abuse must be confirmed through…
Effect of augmented nutrient composition and fertigation system on biomass yield and cannabinoid content of medicinal cannabis (Cannabis sativa L.) cultivation
Abstract Growing evidence underscores the role of nutrients and fertigation systems in soilless production, influencing medicinal cannabis biomass and secondary…
Healthy cats tolerate long-term daily feeding of Cannabidiol
Abstract Cannabidiol (CBD)-containing products are widely commercially available for companion animals, mirroring popularity in human use. Although data on the…
Selenium protects against nesfatin‐1 modulation of the hypothalamic‐pituitary‐testicular axis during hypothyroidism in male rats
Abstract Normal gonadal function can be disrupted by hypothyroidism. Hypothyroidism disturbs testicular function directly and centrally by affecting the hypothalamic‐pituitary‐testicular…
Functionally-selective inhibition of threshold sodium currents and excitability in dorsal root ganglion neurons by cannabinol
Abstract Cannabinol (CBN), an incompletely understood metabolite for ∆9-tetrahydrocannabinol, has been suggested as an analgesic. CBN interacts with endocannabinoid (CB)…
Integrated transcriptome and cell phenotype analysis suggest involvement of PARP1 cleavage, Hippo/Wnt, TGF-β and MAPK signaling pathways in ovarian cancer cells response to cannabis and PARP1 inhibitor treatment
Abstract Introduction:Cannabis sativa is utilized mainly for palliative care worldwide. Ovarian cancer (OC) is a lethal gynecologic cancer. A particular…