Abstract Background: ADP-ribosylation factor-like 4 A (ARL4A), a small GTPase involved in cytoskeletal dynamics and signal transduction, exhibits dysregulated expression…
Abstract Diabetes Mellitus (DM) is a serious medical condition that impacts the lives of millions of people around the world.…
Abstract Acquired or innate lack of response to standard HER2-targeted therapies remains a clinical issue in patients with HER2-positive breast…
Abstract Background: Medical cannabis has gained increasing attention globally for its potential in treating various conditions. As the use of…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-51639-z. Article type: Research Article Keywords: Drug discovery, Medical…
Abstract RAD18, a key E3 ubiquitin ligase implicated in DNA repair and genome stability, is tightly linked to cancer malignant…
Abstract Cancer progression is accompanied by significant metabolic alterations. We developed a novel computational approach to identify cancer-related risk metabolic…
Abstract Tetradenia riparia (Hochst.) Codd is a medicinal plant widely used in traditional medicine. However, comprehensive studies integrating its chemical…
Abstract As a traditional Chinese herbal medicine, Cannabis sativa holds broad prospects for application in the development of functional foods,…
Abstract Background: Imbalance in gut microbiota (GM) may play a role in the development of thyroid cancer (TC), but the…